LightSwitch Pathway Reporter Stable Cell Lines

LightSwitch Pathway Reporter Stable Cell Lines perform exceptionally in primary screens in 96-, 384-, and 1536-well format, and provide consistent, robust results.

Figure 1: Dose response of AhR HepG2 and AhR HEK293 stable cell lines to increasing concentrations of omeprazole.
The AhR HepG2 and AhR HEK293 stable cell lines were assayed for RenSP luciferase following treatment with omeprazole. The HEK293 cell line shows a weaker response to omeprazole than the HepG2 cell line because HEK293 cells express a lower level of the aryl hydrocarbon receptor (AhR).