Sequence Variant Assay Services
1.) You identify the promoters and 3’UTRs of interest.
2.) You specify the variants you want to have created. *
3.) We create variant versions of the promoters or 3’UTRs in a LightSwitch reporter vector.
4.) We transfect the reporter constructs into living cells.
5.) We measure luciferase activity and process the data.
*You may choose individual SNPs or mutated motifs. We can also create clones from individual genomic samples for haplotype studies