Lightswitch miRNA Mimics and Inhibitors


Four validated 3’UTR targets of miR-155 and two negative control reporter vectors were co-transfected with 50nM of miRNA mimic or a non-targeting control miRNA in K562 cells. The knockdown of each vector was calculated as the log2 ratio of miR-155 signal divided by the NTC signal. The four known 3’UTR targets of miR-155 show a strong knockdown compared to the two negative control vectors.


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