Synthetic miRNA Target GoClone Reporters
SwitchGear’s synthetic miRNA target GoClone Reporters contain sequence repeats that are fully complementary to a variety of human and human viral miRNAs. In contrast to our endogenous 3'UTR reporters, each synthetic clone consists of an optimized target sequence cloned downstream of the novel RenSP luciferase that can be used to study miRNA to target interactions. In addition, our synthetic GoClone Reporters can help determine the levels of natural miRNA expression in your cell line.
Applications
- Use as a positive control in miRNA target validation studies
- Use as a biosensor to measure relative levels of endogenous miRNA in your cell line
- Use to determine whether a mimic or inhibitor experiment will be more appropriate in your cell line of interest