Promoter Reporter GoClone Collection Description
Our collection includes sequence-verified and transfection-ready luciferase reporter constructs for over 17,000 human promoters. Measure the functional response of promoters to stimulus in nearly any cell-based system.
Applications
Measure promoter activity to:
- Understand the mechanism by which a gene is induced or repressed
- Characterize the functional consequences of transcription factor binding
- Screen full regulatory networks with SwitchGear’s Pathway Screening Panels
- Measure the effect of sequence variants on promoter function (see our Sequence Variant Assay Services)
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Using high-throughput promoter reporter assays to examine regulatory pathways |
Promoter Reporter Technology
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The SwitchGear Advantage
- Quantitative: Measure promoter activity in response to stimuli using a highly quantitative luciferase assay
- Simple and quick: Perform your experiments today through simple transfection of our luciferase reporter constructs. No cloning or DNA preparation is needed.
- Comprehensive and verified: Choose from SwitchGear’s complete set of sequence-verified and transfection-ready promoter targets
- Functionally insightful: Learn about the actual effects of transcription factor binding to verify computational predictions and supplement microarray or sequencing data.
- Cost-effective: Screen for promoter activation and repression under a multitude of conditions efficiently.