UTR Reporter GoClone Collection Description

Sequence-verified and transfection-ready luciferase reporter constructs for over 11,000 human 3’UTRs. Measure RNA stability, translation efficiency and the functional impact of miRNAs on a gene-by-gene basis.

Applications

Measuring 3’UTR activity characterizes:

  • The impact of the UTR in post-transcriptional gene regulation
  • The impact of a miRNA or siRNA on the regulation of transcript stability or translation efficiency
  • The effect of sequence variants on UTR function (see our Sequence Variant Assay Services)
smallgraphic-technicalnote High-throughput microRNA Target Screening: miR-122 Case Study
smallgraphic-poster High-throughput microRNA Target Screening: miR-122 Case Study
UTR Technology
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The SwitchGear Advantage

  • Quantitative: Measure miRNA, siRNA, and UTR impact on gene regulation through luciferase activity.
  • Functionally insightful: Learn about the actual functions of miRNAs to verify computational predictions and supplement expression data with measurement of transcript regulation and translational efficiency.
  • Comprehensive and validated: Choose from Switchgear’s transfection-ready catalog of 7,000 sequence-verified UTR constructs.
  • Simple and quick: Perform your experiments today through simple transfection of our UTR-luciferase constructs. No cloning required.
  • Cost-effective: Understand the function of your favorite miRNAs in response to various stimuli efficiently.